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GI: diarrhea, abdominal pain, nausea, flatulence, dry mouth, vomiting, constipation. Amoxicillin, clarithromycin: Increases esomeprazole levels. Monitor patient for toxicity. Diazepam: Decreases diazepam clearance. Monitor patient for diazepam toxicity. Other drugs metabolized buu cytochrome P-450 2C19: Alter esomeprazole clearance.
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